This study examined whether the Ramp-Up to Readiness program (Ramp-Up) differs from college readiness supports that are typically offered by high schools, whether high schools were able to implement Ramp-Up to Readiness to the developer's satisfaction, and how staff in schools implementing Ramp-Up to Readiness perceive the program. The researchers conducted interviews and focus groups with staff in two groups of schools: (1) a group of 10 schools that were in the first year of implementation of Ramp-Up to Readiness, and (2) a group of 10 other schools that were not implementing the program. The researchers also administered surveys to staff employed by these 20 schools as well as to students in grades 10–12 in these schools. Through these data collection efforts, the researchers obtained information on the types of college readiness programming and supports in the two types of schools, students' perceptions of college-focused staff-student interactions, schools' success at implementing Ramp-Up to Readiness' core components and sub-components, and the opinions of staff in implementing schools about the program. Compared with non-Ramp-Up schools, those implementing Ramp-Up offered more college-oriented structural supports, professional development, and student-staff interactions. Ramp-Up schools also made greater use of postsecondary planning tools. Students in Ramp-Up schools perceived more emphasis on four of five dimensions of college readiness than students in comparison schools. Ramp-Up schools met the program developer's threshold for adequate implementation on four of five program components (structural supports, professional development, curriculum delivery, and curriculum content). However only 2 of the 10 schools met the developer's adequacy threshold for the other component (use of postsecondary planning tools). Staff at Ramp-Up schools generally had favorable perceptions of the program. Schools that implement Ramp-Up were able to offer deeper college readiness support to more students than comparison schools. Schools that adopt Ramp-Up can implement the program as intended by the program developer, but some program components are more challenging to implement than others. Additional studies should be performed to examine whether implementation improves after a second year of implementation and whether Ramp-Up improves the likelihood that students will enroll and succeed in college.