In this announcement, the Institute of Education Sciences (Institute) requests applications to its new Partnerships and Collaborations Focused on Problems of Practice or Policy grants program (Collaborations Program). Through the Collaborations Program the Institute seeks to improve the quality of education for all students through advancing the understanding of and practices for teaching, learning, and organizing education systems. This research is to be done in through close collaboration with practitioners and policymakers1 through the partnering of researchers with U.S. State and local education agencies. Grants are to be provided under three topics: