In this announcement, the Institute of Education Sciences (Institute) requests applications to its Partnerships and Collaborations Focused on Problems of Practice or Policy grants program (Research Collaborations Program). The program is intended to support research that is carried out by research institutions and U.S. state and local education agencies working collaboratively on problems or issues that are a high priority for the education agencies. The research may focus on students within a wide range of education settings from prekindergarten through postsecondary and adult education, and may focus on typically developing students and/or students with or at risk for disability. The goal of this research grant program is the improvement of education outcomes for all students, particularly those at risk of failure.