In this announcement, the Institute of Education Sciences (Institute) requests applications for its Low-Cost, Short-Duration Evaluation of Special Education Interventions (Low-Cost Evaluation) grant program. The program is designed to support rigorous evaluations of interventions that state and/or local education agencies (or other state or local agencies that oversee early intervention services) expect to produce meaningful improvements in education outcomes for infants, toddlers, children, and youth with or at risk for a disability within a short period (for example, within a single semester or academic year). These evaluations are to be conducted for $250,000 or less and completed within two years. The program will be carried out by research institutions and state or local agencies working together as partners. The evaluations will use randomized controlled trials, regression discontinuity designs, or single-case experimental designs to determine the impact of interventions on education outcomes for infants, toddlers, children and youth, and will rely on administrative data or other sources of secondary data to provide measures of these education outcomes.