In this Request for Applications (RFA), NCER invites applications for research projects that will contribute to its Transformative Research in the Education Sciences Grants program (CFDA 84.305T). This program supports innovative or unconventional research that has the potential to lead to new scientific paradigms, novel and more effective approaches to education practice or policy, or transformative technologies that substantially increase learner outcomes. Such innovation may require perspectives and experiences not typically represented in education research, and for that reason, applications are sought that reflect the full diversity of the nation’s research workforce. Individuals from diverse backgrounds and from the full spectrum of eligible institutions in all geographic locations are strongly encouraged to apply to this program.