The project team will develop a prototype of a virtual reality (VR) escape room for middle and high school biology to engage students in a problem-based, interactive, multi-modal collaborative learning environment. The team will create a teacher dashboard to capture student progress. Researchers will carry out a pilot study at the end of Phase I with six educators and 24 students in grades 9 and 10 to test if the prototype functions as planned, if educators believe that the escape room can be integrated within classroom practice, and if students are engaged and show improvements on a pre-to-post-test on NGSS-aligned measures of learning high school biology content.