This protocol guides the review of research that informs What Works Clearinghouse (WWC) reports in the area of Supporting Postsecondary Success. This area focuses on interventions for postsecondary students that aim to support postsecondary success, with a primary focus on improving student outcomes during and after college. Thus, programs may be focused on improving the academic performance of students while attending college, increasing the number of students who transfer from 2- to 4-year colleges or attain a degree or certificate, or improving post-college labor market outcomes. This area may include instructional programs that occur in-person or online as part of postsecondary schooling, out-of-classroom practices such as mentoring, classroom practices such as strengths-based learning, adult education activities, and any other strategy focused on supporting student success in college. Within this framework, a number of broad intervention strategies are relevant, including summer bridge programs, first year experience programs, supplemental instruction, tutoring and mentoring.