This guide is intended to help state education agency, school district, and school staff review research studies to identify high-quality evidence-based interventions that meet their needs. It provides considerations under four main topics: (1) Study source, (2) Study design, (3) Study findings, and (4) Study relevance. For each topic, the guide discusses elements to look for in a study, questions to ask about each element, why it matters to consider each element, implications, and resources.